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Dienolone

This is a discussion on Dienolone within the Q & A with Patrick Arnold forums, part of the Supplements Discussion category; I'm sure this has been discussed before but what's up with this stuff? Is it a dry or wet compound ...

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    Dienolone


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    I'm sure this has been discussed before but what's up with this stuff? Is it a dry or wet compound and how is it effective? I have heard some people say it increases estrogen, decreases appetite, etc. Other people love it. Thoughts on trenazone?

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    Patrick covers this in his blog.

    Here's the excerpt:

    The first compound is estra-4,9-diene-17b-ol-3-one (commonly referred to as “dienolone”). What is ironic about this compound is that the government scheduled it’s precursor (estra-4,9-diene-3,17-dione - erroneously referred to as “tren”) just last January. If you recall, the old “tren” products worked pretty well but at the same time they were not free of potential adverse side effects. Anyway, as effective a compound as tren was, expect this stuff to work a lot better – and for two reasons. First reason, this is the active hormone and so requires no in-vivo enzymatic conversion. Second reason, this is delivered in a transdermal base so bioavailability goes way up as compared to oral. This product scores an impressive 10:1 on the Hershberger anabolic/androgenic ratio scale, plus it’s got decent absolute anabolic potency. As of yet I have not heard of anyone using it and I don’t know if it has hit the shelves yet.
    More info would be nice though, because I don't have access to any online articles for dienolone. Maybe anabolics 10th edition has it
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    Quote Originally Posted by BrYmAsTeR17 View Post
    Patrick covers this in his blog.

    Here's the excerpt:



    More info would be nice though, because I don't have access to any online articles for dienolone. Maybe anabolics 10th edition has it
    sadly the 10th edition does not cover it. as soon as I read your post I ran to it and flipped to the profiles and its not there!

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    Quote Originally Posted by owen_z View Post
    sadly the 10th edition does not cover it. as soon as I read your post I ran to it and flipped to the profiles and its not there!
    goddamit that sux. What's in that book anyway? I ordered it a little while ago
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    oh laaawdddd. well, starts out with history of testosterone, basic chemistry and structures, treatments with steroids, big steroid and designer steroid glossary with ALOT of stuff (just no dienolone) proper PCT, bloodwork readings, cycle setups and how to spot counterfeits. theres a whole like 15 page color section dedicated to spotting fakes.

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    Quote Originally Posted by henryv View Post
    What do you want to know? It's basically like the PH tren, just active without needing conversion.
    Well thanks captain obvious, hahaha i'm kidding. I just want to know more about dienolone's history. How it was formulated, why it was made, it's structural differences and outcomes of these differences..etc.etc.
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    Quote Originally Posted by owen_z View Post
    oh laaawdddd. well, starts out with history of testosterone, basic chemistry and structures, treatments with steroids, big steroid and designer steroid glossary with ALOT of stuff (just no dienolone) proper PCT, bloodwork readings, cycle setups and how to spot counterfeits. theres a whole like 15 page color section dedicated to spotting fakes.
    oh, great does it have info on compounds and diagrams and such?
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    each compound they have listed goes into detail about its origin, administration, side effects, use in women and what manufacturers are still producing them. not much for diagrams other than the cycle planner. which might I add also shows how to cycle dbol only and anadrol only safely even though its against alot of everyones principles.

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    Quote Originally Posted by owen_z View Post
    each compound they have listed goes into detail about its origin, administration, side effects, use in women and what manufacturers are still producing them. not much for diagrams other than the cycle planner. which might I add also shows how to cycle dbol only and anadrol only safely even though its against alot of everyones principles.
    awesome! thanks owen, can't wait to get mine.
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    i went the extra buck to get the hardcover and ordered from moleculars website because that was before i realized we had it here in store!! lol its a shame though there is no details on the straight dienolone. they do discuss bolasterone

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    Quote Originally Posted by owen_z View Post
    i went the extra buck to get the hardcover and ordered from moleculars website because that was before i realized we had it here in store!! lol its a shame though there is no details on the straight dienolone. they do discuss bolasterone
    yeah, i'm gonna have my head in that book for the next few months. William llewellyn is a good source
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    doesn't sound too different than anabolics 9th edition.

    seth roberts anabolic pharmacology I believe has a dienolone profile in it.
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    so how would you expect the results to differ from x-tren? i dont really like the fact that trenazone is a transdermal though

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    Quote Originally Posted by henryv View Post
    You can find it in this paper from 1960: A NEW CLASS OF ACTIVE STEROIDS: THE 19-NOR-[UNK]4,9-3-KETOSTEROIDS - Journal of the American Chemical Society (ACS Publications)

    It was studied for A:A activity just like hundreds of others in the 1960s. Structurally it's just the active (17b-ol) version of the steroid, where "tren" is the dione. The outcome is that it's already active without needing conversion by 17b-HSD. Personally I don't think it will be a ton stronger, since I think tren converts very well into dienolone.
    Hey thanks for showing where it's at. I can bookmark it now, sweet. Does this article describe dienolone's bioavailability? Or did Antaeus just pull that 6% figure out of the sky?
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    Quote Originally Posted by henryv View Post
    I think they used a figure for general oral steroid application. I think the oral bioavailability of tren and dienolone is likely to be higher due to the specifics of their metabolism.
    And their metabolism being similar to other 19-nors?
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    synthesized as shown in Scheme 1. β-Estradiol (12) was protected as the methyl ether (13) and subjected to Birch reduction22 to afford the unconjugated diene. Deprotection of the ether under acidic conditions was followed by bromination and dehydrobromination to yield dienone
    This process may be the reason they named it "dienolone"
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    Quote Originally Posted by henryv View Post
    Similar to trenbolone. Not so similar to nandrolone.
    gotcha

    Quote Originally Posted by henryv View Post
    It's called dienolone because it is a diene, with an "ol" (alcohol, hydroxyl) and a "one" (a ketone). Just like boldenone is called boldenone because it's a "(17)b-ol" "d(i)en(e)" "one".
    oh, cool thanks for that
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    hmmm I am considering running a trenazone + havoc stack this summer so I am really reading up on dienelone and putting my budget together. Should be a pretty sick stack looking at 6 weeks all the proper supports, bloodwork, and a vicious PCT. I will be cutting until right before the stack so if everything goes according to plan it will be a nice clean bulk to add 5-10 lbs of lbm to my frame.

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    Quote Originally Posted by BrYmAsTeR17 View Post
    Well thanks captain obvious, hahaha i'm kidding. I just want to know more about dienolone's history. How it was formulated, why it was made, it's structural differences and outcomes of these differences..etc.etc.

    it was never developed by any drug company as a steroid for market. ethyldienolone almost made it to the market though
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    Quote Originally Posted by henryv View Post
    It's called dienolone because it is a diene, with an "ol" (alcohol, hydroxyl) and a "one" (a ketone). Just like boldenone is called boldenone because it's a "(17)b-ol" "d(i)en(e)" "one".

    why is DHT called Baldenone then?
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    Quote Originally Posted by Patrick Arnold View Post
    it was never developed by any drug company as a steroid for market. ethyldienolone almost made it to the market though
    Oh, yeah i guess they felt there was no purpose for it. Maybe because trenbolone already filled that medical "spot", since they are so similar
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    Quote Originally Posted by Patrick Arnold View Post
    why is DHT called Baldenone then?
    hah!
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    Quote Originally Posted by BrYmAsTeR17 View Post
    Oh, yeah i guess they felt there was no purpose for it. Maybe because trenbolone already filled that medical "spot", since they are so similar
    it probably was patented by a drug company that had several anabolic steroids patented and they decided to go with another steroid to market. Since they had the patent on it that would preclude others from selling it.
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    Quote Originally Posted by Patrick Arnold View Post
    it probably was patented by a drug company that had several anabolic steroids patented and they decided to go with another steroid to market. Since they had the patent on it that would preclude others from selling it.
    ah so they could hide it for a while and keep it safe, just in case other steroids became a "bad patent" or useless. Looks like that never happened, in retrospect, since there is so little info on dienolone (especially online). Or if it did happen, not till now lol
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    Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute Patrick Arnold has a reputation beyond repute
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    Quote Originally Posted by BrYmAsTeR17 View Post
    ah so they could hide it for a while and keep it safe, just in case other steroids became a "bad patent" or useless. Looks like that never happened, in retrospect, since there is so little info on dienolone (especially online). Or if it did happen, not till now lol

    not quite. no one was hiding anything. patents are public documents.

    drug companies patent thousands and thousands of compounds knowing that only a few will ever make it to market. all the others are patented simply to keep them out of the hands of competitors.
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