By Reggie Johal
Reggie Johal is a published author on nutrition and supplements, as well as international athlete and coach to many sportsmen and women.
Prohormones - A Comprehensive Guide to Prohormones - Updated
Halodrol- 50 (4-chloro-17a-methyl-1,4-diene-3,17 diol)
Halodrol-50 was introduced to the bodybuilding world by Gaspari Nutrition and is a prosteroid of Turinabol, the banned East German designer steroid. This means it converts to Turinabol once ingested. Although Halodrol is no longer available, there are generic equivalents today such as Competitive Edge Labs H-Drol or EST Hemadrol. The typical dose for products such as H-Drol is 50mg a day, which equates to one tablet daily.
Effects: Solid gains in muscle and strength, often taken while dieting to aid preservation of muscle mass.
Side effects: Considered stressful on the liver and can raise blood pressure somewhat in users.
RPN's product Havoc and IBE's Epistane were introduced at practically the same time and considered interchangeable by many. However, it should be noted that even when two products are identical, users can experience different effects depending on the quality of the isomer, manufacturing process and so on.
With Havoc and Epistane they are chemically very slightly different 2a,3a-epithio-17a-methyl-5a-androstan-17b-ol 2 (Havoc), and 2, 3a-epithio-17a-methyletioallo cholan-17b-ol (Epistane). Dosages are usually in the 20-50mg range.
Effects: Good for promoting solid, lean muscle gains with a concomitant reduction in estrogen leading to a drier physique, and significant strength gains. This will contribute to the vascularity users typically report. Havoc and Epistane are also sometimes used purely to combat gynecomastia as they act in the body as an anti-estrogen, so that endogenous testosterone levels are less suppressed by this compound than other prohormones.
Side effects: Less hepatoxic and damaging to lipid levels than other orals but the usual androgenic side effects associated with prohormones remain a possibility.
Pheraplex was a brand name of the supplement company Anabolic Xtreme (AX). This product is also sold by Competitive Edge Labs as P-Plex as well as Phera-Vol by EST. Typically dosed at 20-30mg a day.
Effects: Gains with this product tend to be of a 'wet' nature, in other words, you will see some weight gain due to water retention. Given this, P-Plex is often used to gain mass quickly for users.
Side effects: It is a risk for anyone with gynecomastia based on user feedback and is considered to be both hepatoxic and damaging to lipid levels.
This product was brought to the market by Bioscience Technologies and is usually dosed at 6-12mg to see results.
Effects: Not a strong bulking product unless doses are pushed high despite its androgenic profile. In this respect it is not dissimilar to AAS such as Masteron and Proviron which are not efficient for bulking.
Side effects: Androgenic side effects such as hair loss are reported quite frequently by users if this product, and many users report a damaging effect on libido.
Ergomax LMG (17-methyl-delta-2-etioallocholane & 17-methyl-delta-3-etioallocholane)
Introduced by ALRI, this is another 'wet' prohormone dosed at 20-40mg usually.
Effects: This compound is quite similar to Pheraplex so is useful for someone wanting to gain mass quickly even if the visual appearance of this will not be the best.
Side effects: Can cause gynecomastia making use of an estrogen blocker a wise option, and has a detrimental effect on liver and lipid values, meaning cycles should be kept short.
M-1,4ADD has recently been reintroduced by Competitive Edge Labs among others and is from the old school of prohormones â€“ a classic wet bulker which converts after ingestion into Methandrostenolone, better known as Dianabol.
Effects: This is a good choice for rapid mass and strength gains but the gains will tend to cause smoothness due to the water retention it causes.
Side effects: This compound can promote both androgenic and estrogenic side effects so anyone with a predisposition to hair loss or gynecomastia should probably avoid this.
11-Oxo (andrenosterone, 11-oxo-androstenedione)
11-Oxo was introduced by Ergopharm, whose owner Patrick Arnold first brought prohormones to the bodybuilding world. 11-Oxo is well regarded for its ability to lower cortisol levels. It is dosed at between 300-600mg a day with 450mg typical.
Effects: Used mainly as a recomposition agent and to promote fat loss, 11-OXO is also a good choice for individuals looking to stack one prohormone with another.
Side effects: Although it can cause the same side effects as other prohormones, it is considered very mild in this regard so a good choice for people looking to diet with minimal side effects.
This was developed by EST Nutrition and is usually dosed at 90mg a day.
Effects: Noted to be good for reducing body fat and for promoting rapid strength and muscle gains.
Side effects: Relatively mild with this compound, although those who worry about gyno or androgenic side effects should exercise caution. Tends to be expensive!
ALRI introduced this compound and it is dosed at 3-6mg by most users.
Effects: Reviews are mixed on this product but those who do like it often claim very good muscle and strength gains allied to a reduction in body fat.
Side effects: Being both quite androgenic and estrogenic it should be used with caution and remedies to combat hair loss and gyno are worth considering.
Max LMG (13-ethyl-3methoxygona-2, 5(10)-dien-17-one)
Yet another product by ALRI. This one is usually dosed at around 100mg a day.
Effects: Max LMG can cause rapid gains in bulk of a wet nature due to its progestogenic nature. Great for those needing fast weight gain and unconcerned about looking smooth or fat.
Side effects: One to avoid for anyone worried about a quality looking physique, gynecomastia, or hair loss. This is also very expensive!
3-AD (2-androstenol acetate)
Anabolic Xtreme formulated this product and brought it on to the bodybuilding market. Usually dosed at around 4-6 capsules a day, 3-AD contains various other nutrients, but the active prohormone is 2-androstenol acetate.
Effects: Effective overall mass gainer. Gains are a little wet, but not too bad for those worried about estrogen.
Side effects: It is not the worst, but estrogenic and androgenic side effects remain a possibility.
Superdrol was introduced by Designer Supplements, the old name for Driven Sports, and earned a reputation as a very powerful product. Although it is no longer made by Driven Sports, Competitive Edge Labs currently produce a clone called M-Drol.
Effects: Good lean mass gainer with effective repartitioning effects.
Side Effects: Notably hepatoxic, and androgenic. Can aggravate hairloss if prone to male pattern baldness. Highly recommended to stack this product with a product from our Liver Support category to help support healthy liver function.
Dymethazine - (2,17-dimethyl-5-androstan-17-ol-3,3'-azine)
Dymethazine, also known as Dimethazine, is a DHT derived compound with an interesting chemical structure. It is essentially a double bonded Superdrol, with an Azine bridge. A relatively recent introduction to the prohormone world by I Force Nutrition, Dymethazine is a product that has attracted a great deal of interest given its unique chemical structure.
Effects: Users of this compound are reporting results that are qualitatively similar to dry, non-aromatizing products such as Epistane. Dymethazine users have typically reported big muscle and strength gains. Based on feedback to date Dymethazine looks to be the strongest product available on the market today.
Side Effects: Although not having any estrogenic action, Dymethazine use poses the same issue of liver toxicity and androgenic effects as other prohormones.
The One â€“ (17a-methyl-etioallocholan-17b-ol-3-hydroxyimine)
The One was developed by Applied Nutriceuticals and is a prohormone of Dihydrotestosterone.
Effects â€“ Being a prohormone to DHT, The One can be expected to be notably androgenic, resulting in dry, muscle gains with an absence of water retention and solid gains in strength.
Side Effects â€“ Being that it converts into DHT, The One can be expected to be tough on the hairline as DHT is the hormone most responsible for hair loss. As it does not convert to estrogen or progesterone, side effects related to those should not be an issue. Liver toxicity would remain a concern though and it would be a good idea to take this product with something to support health liver function.
1,4 AD Bold 200 â€“ (1, 4 Androstadiene-3, 17- Dione 200mg)
Made by I Force Nutrition, 1,4 Bold 200 is a precursor to the compound Boldenone (Equipoise) which has a very long history of use in bodybuilding circles and is highly regarded for its ability to increase muscle mass with minimal side effects.
Effects - Bold 200 has the advantage of being non-methylated making it a first choice along with Furazadrol, or Finavol for newcomers to the prohormone field. Users typically can expect to notice improved muscle gains which will come steadily and less dramatically than other compounds, as well as an improved appetite and increase in vascularity.
Side Effects â€“ There is a comparatively low risk of both androgenic or estrogenic side effects and being non-methylated makes it an ideal choice for those concerned with liver health. It also makes it ideal for use in a stack with stronger, methylated prohormones such as dymethazine.
Finavol â€“ ( Estra-4,9-diene-3,17-dione)
Sold by a number of different brands, including Competitive Edge Labs (X-Tren), and Chaparral Labs (Trenavol) Finavol is APS Nutritionâ€™s version of this compound. This product has Nandrolone as a target hormone and is non-methylated, making it safer on the liver and an excellent choice as part of a prohormone stack.
Effects â€“ Finavol is well suited to athletes looking for muscle gains with an increase in vascularity and strength that are compared as qualitatively similar to the compound Trenbolone.
Side Effects â€“ Nandrolone precursors can negatively impact upon libido in some people.
Furazadrol â€“ (5a-androstano(2,3-c) furazan-17b-tetrahydropyranol ether - 50mg)
Furazadrol was developed by Axis Labs as an alternative to methylated prohormones such as Havoc or Dymethazine. As a non-methylated compound it will appeal on the grounds of being very safe and is often used by beginners new to prohormones either alone or in a stack with Bold 200.
Effects â€“ Furazadrol has a high anabolic to androgenic ration meaning muscle gains with low risk of androgenic side effects. It does not convert to estrogen meaning gains will be lean in nature, with an absence of water retention.
Side Effects â€“ Although the risk of side effects is low, it is usually required to be dosed in dosages of 200-400mg a day making it quite expensive. Given its otherwise favourable profile it makes an excellent choice for someone looking to stack with another prohormone.
Edited by Holden Caulfield, 09 December 2009 - 03:42 PM.