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#1 truthornothin

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Posted 24 January 2014 - 10:02 AM

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TestForce 2 is an all natural testosterone elevator formulated to maximally stimulate the natural production of testosterone and growth hormone. This product contains the most soluble form of D-Aspartic Acid combined with another remarkable amino acid known as Sarcosine. This combination provides a product unparalleled to other D-Aspartic Acid supplements on the market. This highly soluble powder dissolves nearly instantly and with its delicious slightly sweetened fruit punch flavor you’ll not only enjoy the taste, but the results. Consume two scoops twice a day for three weeks. Afterwards consume one scoop twice a day. Daily use of TestForce 2 as directed will lead to a gradual elevation in Testosterone that peaks in approximately three to five weeks, continued use maintains peak testosterone levels.


The science: When d-aspartic acid (DAA) is ingested it is absorbed into the body and taken up preferentially by endocrine tissues such as the hypothalamus, pituitary, and testicles. There it stimulates the activity of what are known as NMDA receptors. NMDA receptors are located on neurons and they regulate neuronal activity. DAA binds to a specific docking site (receptor) located on the NMDA receptor known as NMDA binding site.

In the hypothalamus the stimulation of NMDA receptors leads to the production of gonadotropin releasing hormone (GnRH) which stimulates the pituitary gland to release luteinizing hormone (LH) and follicle stimulating hormone (FSH). LH and FSH travel to the testicles to initiate the process of steroidogenesis, which leads to the release of testosterone into the blood stream. Stimulation of NMDA receptors in the hypothalamus also leads to the release of growth hormone releasing hormone (GHRH) which promotes the release of growth hormone from the pituitary gland.

The more you activate the NMDA receptor in the hypothalamus the greater the release of GnRH and GHRH, and ultimately testosterone and growth hormone.

The NMDA receptor is somewhat unique in that it requires activation by two ligands (a ligand is like a “key” to a receptor). In the hypothalamus the main ligand for the NMDA receptor is d-aspartic acid. The secondary ligand (or co-activator) is the amino acid glycine. Both DAA and glycine have specific binding sites on the NMDA receptor. These sites are known as the NMDA binding site and the glycine binding site respectively. Think of it this way - just like how firing a nuclear missile requires two soldiers to turn two separate keys, so the NMDA receptor requires binding by two ligands to initiate its influence on the firing of a neuronal signal.

So to review, administration of DAA leads to it’s uptake into the hypothalamus and binding to the NMDA receptors there. And to activate the NMDA receptor you also require adequate levels of ligands that bind to the glycine site of the NMDA receptor. Now common sense would lead one to assume that by ingesting supplemental amounts of glycine would ensure that glycine site co-activation is ensured. However the scientific literature has shown that this method has limited efficacy.

The reason that glycine administration is not very effective at stimulating NMDA activity is not completely straight forward, but one reason is because it is efficiently removed from the synapses by the reuptake regulator Glycine Transporter 1 (GT1).

Interestingly, much of the science published on the subject of stimulation of NMDA receptor activity revolves around the theory that NMDA receptor hypo-activity is a causative factor in schizophrenia. For years scientists have been investigating ways to stimulate NMDA activity as a means for treating schizophrenic patients. One of the most effective strategies has been through targeting the GT1 protein. And one of the most efficient means to do this is actually through supplementation with sarcosine.

Of course we aren’t concerned about treating schizophrenia here, what we are concerned with is maximally stimulating natural production of testosterone (or growth hormone). But the mechanism in question is exactly the same for both purposes. By blocking the re-uptake of glycine you increase the concentration of glycine in neuronal synapses, and therefore increase the influence of NMDA upon nerve transmission. In essence this is the exact way some anti-depressants (such as SSRIs) work, except the goal there is to increase binding and activating of serotonin or dopamine receptors, not NMDA receptors.

Blocking glycine reuptake is not the only mechanism through which sarcosine stimulates DAA activity. Sarcosine actually can itself bind to the glycine binding site of NMDA receptors. In fact, it binds with a higher affinity than even glycine. So basically it replaces glycine as well as serves as its own reuptake inhibitor. It totally solves the glycine co-activation issue in one shot.

Knowing all these facts you can see why sarcosine produces a rather dramatic effect on NMDA neuronal transmission compared to glycine itself, or other endogenous ligands for the glycine receptor such as d-serine.

To summarize, for d-aspartic acid to work to its maximum potential it must be taken with an efficient stimulator of the glycine binding site on the NMDA receptor. The most efficient non-drug stimulator we know of is the natural amino acid sarcosine.

TestForce2 contains 3 grams of d-aspartic acid (as d-aspartate calcium chelate) and 3 grams of sarcosine per serving.

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#2 truthornothin

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Posted 24 January 2014 - 10:08 AM

finally getting around to replacing the lost stickies Board Administrator/Henry make sticky please

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#3 Quadzilla99

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Posted 30 January 2014 - 05:59 AM

I got two of these coming from NP. I'm taking it mainly as a nootropic as that neuron dude ranked DAA and Sarcosine as like two of the best nootropics

#4 3clipseGT

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Posted 30 January 2014 - 12:27 PM

I got two of these coming from NP. I'm taking it mainly as a nootropic as that neuron dude ranked DAA and Sarcosine as like two of the best nootropics


I definitely notice that when i take TestForce 2 prior to a workout im much more focused than if i dont take it.
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#5 seabiscuit hogg

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Posted 30 January 2014 - 07:59 PM

I definitely notice that when i take TestForce 2 prior to a workout im much more focused than if i dont take it.

Sarcosine stimulates acetylcholine receptors including the nicotinic one. This has a profound effect on lifts.

#6 truthornothin

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Posted 31 January 2014 - 10:18 AM

Sarcosine stimulates acetylcholine receptors including the nicotinic one. This has a profound effect on lifts.

it is part of my pre workout regimen too. Its Clearshot original(opened my last half gallon today sob) testforce2, taa and cop. On leg days I add keto force. It is the most potent stack you'l find.

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#7 seabiscuit hogg

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Posted 31 January 2014 - 11:41 AM

it is part of my pre workout regimen too. Its Clearshot original(opened my last half gallon today sob) testforce2, taa and cop. On leg days I add keto force. It is the most potent stack you'l find.

Can't get clearshot original, there is another prewo option tho, so I can do something pretty close to that stack.

#8 truthornothin

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Posted 31 January 2014 - 07:49 PM

Can't get clearshot original, there is another prewo option tho, so I can do something pretty close to that stack.

Yes just supply your own stimulant, the new AMP Should be out soon, its been delayed

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#9 seabiscuit hogg

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Posted 12 March 2014 - 05:34 PM

Yes just
supply your own stimulant, the new AMP Should be out soon, its been delayed

I'm taking huperzine a now, for my memory. The effect on lifting is quite amazing. I can hardly wait to see how it works with testforce2.

#10 seek2bhappy

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Posted 12 March 2014 - 07:00 PM

Even though I could buy DAA bulk powder this product is wayyy better.

It's like driving a mustang vs a civic. Both reliable options but you get what you pay for.

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#11 truthornothin

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Posted 12 March 2014 - 07:26 PM

Even though I could buy DAA bulk powder this product is wayyy better.

It's like driving a mustang vs a civic. Both reliable options but you get what you pay for.

Yep the difference is definitely noticeable, I've used both bulk and Testforce2. When I use Testforce2 I almost always awake with the morning wood. Not so with the bulk stuff...as I near 50 its a nice benefit...it makes me feel young again and doesn't happen without it

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#12 southernmuscle

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Posted 25 August 2014 - 01:23 PM

Would Testoforce 2 be good product to add into a PCT program?   Since the studies show that it helps the body produce both LH and FSH it would appear that it would not only increase test production but sperm production also. Correct me if I'm wrong on my theory but it seems like it would work synergisticly with a traditional PCT program of HCG and clomid.  Therefore someone suffering from AAS induced azoospermia would benefit from supplementation with Testoforce 2.



#13 gtsmike

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Posted 25 August 2014 - 01:42 PM

absolutely.

 

i always use it in my pct regimen.

 

alot of ppl on here do as well.


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