Sorry bro, I wasn't singling you out or anything. I saw seabiscuitt's too, I just didn't want to multi quote and make it into a long post. I simply quoted you because yours was on the same page I was replying on. I just used yours to use as an example for anyone else doubting 1-andro.
And now that I look back, I actually missed the part where you said it would just need to be dosed higher...and I agree with that, as far as the TD goes. 1-andro seems to work just fine orally too though.
And I also agree, this is probably like dienazone where it just has to be dosed higher. It reminds me of exactly what you just said, where one guys ran it at 1ml and got nothing, ran it again at 2-3ml and BOOM - best cycle ever! However, TD was actually necessary for dienolone because it has horrible oral BA.
But I do think that being a TD does matter with some compounds though. Sometimes TDs help the multi-step types like 1-andro because apparently the skin has a lot of hormone converting enzymes for the compound to interact with, hence leading to greater conversion to the target hormone. I've never actually looked into this but if it is true...then being a TD should matter for some compounds. Does it matter with 1-andro? Honestly, I don't think so because clearly from that study, taking it orally will give results. So with that, why not apply the same concept to it orally and just up the dose the way you would with a topical.
And TDs don't just have to apply to multi-step compounds, it can be applied to any compound that has poor BA and has a MW small enough to be stable and penetrate through the dermis. But that's another story for another thread.
Again, my apologies on using your quote, it was just for simplicity's sake. People really don't like it when I post long comments, lol.
But if you don't mind me asking...how did you like 1-andro TD? And have you ever taken it orally?